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Publications

  1. Renee M. Fleeman and Bryan Davies. Polyproline Peptide Aggregation with Klebsiella pneumoniae Extracellular Polysaccharides Exposes Biofilm Associated Bacteria. Microbiology Spectrum. March 7, 2022. DOI:10.1128/spectrum.02027-21.

  2. Justin R. Randall, Gillian Davidson, Renee M. Fleeman, Santos A. Acosta, Ian M. Riddington, Timothy J. Cole, Cory D. DuPai, and Bryan W. Davies. Synthetic discovery and development of symbah-1, a macrocyclic beta-hairpin peptide antibiotic. iScience. January 21, 2022. DOI 10.1016/j.isci.2021.103611.

  3. Renee M. Fleeman, Luis Macias, Jennifer Brodbelt, and Bryan Davies. Defining principles that influence antimicrobial peptide activity against capsulated Klebsiella pneumoniae. PNAS. November 3, 2020. DOI 10.1073/pnas.2007036117.

  4. Danielle H. Demers, Matthew A. Knestrick, Renee Fleeman, Rahmy Tawfik, Ala Azhari, Ashley Souza, Brian Vesely, Mandy Netherton, Rashmi Gupta, Beatrice L. Colon, Christopher A. Rice, Mario A. Rodriguez-Perez, Kyle H. Rohde, Dennis E. Kyle, Lindsey N. Shaw, and Bill J. Baker. Exploitation of Mangrove Endophytic Fungi for Infectious Disease Drug Discovery. Marine Drugs. October 10, 2018. DOI 10.3390/md16100376.

  5. Renee Fleeman, Travis M. LaVoi, Radleigh G. Santos, Angela Morales, Adel Nefzi, Gregory S. Welmaker, José L. Medina-Franco, Marc A. Giulianotti, Richard A. Houghten, and Lindsey N. Shaw. The Development of Novel Anti-Resistance Agents Targeting the Efflux Pumps of Multi-Drug Resistant Bacterial Pathogens. Frontiers in Microbiology. June 14, 2018. DOI 10.3389/fmicb.2018.01301.

  6. Renee Fleeman, Kurt S. Van Horn, Megan M. Barber, Whittney N. Burda, Roman Manetsch, and Lindsey N. Shaw. Characterizing the Antimicrobial Activity of N2,N4-Disubstituted Quinazoline-2,4-Diamines Towards Multidrug Resistant Acinetobacter baumannii. Antimicrob. Agents Chemother. March 13, 2017. DOI 10.1021/jm501628s.

  7. Kirkpatrick, Christine, Broberg, Christopher, McCool, Elijah, Lee, Woo Jean, Chao, Alex, McConnell, Evan, Pritchard, David, Hebert, Michael, Fleeman, Renee, Adams, Jessie, Jamil, Amer, Madera, Laurence, Strömstedt, Adam, Goransson, Ulf, Liu, Yufeng, Hoskin, David, Shaw, Lindsey, Hicks, Leslie. "The ‘PRISMS’ pipeline for natural product bioactive peptide discovery". Analytical Chemistry. January 17, 2017. DOI: 10.1021/acs.analchem.6b03625.

  8. Andy Wiess, Renee M. Fleeman, Lindsey N. Shaw. Exposing the Unique Connection between Metabolism and Virulence in Staphylococcus aureus. Cell Chemical Biology. November 17, 2016. DOI: 10.1016/j.chembiol.2016.11.003.

  9. Yangmei Li, Nina Bionda, Renee Fleeman, Hongjie Wang, Akihiko Ozawa, Richard A. Houghten, Lindsey Shaw.  Identification of 5,6-dihydroimidazo[2,1-b] thiazoles as a New Class of Antimicrobial Agents. Bioorganic and medicinal chemistry. November 1, 2016. DOI: 10.1016/j.bmc.2016.09.027.

  10. Jacqueline L. von Salm, Christopher G. Witowski, Renee M. Fleeman, James B. McClintock, Charles D. Amsler, Lindsey N. Shaw, and Bill J. Baker. Darwinolide, a New Diterpene Scaffold That Inhibits Methicillin-Resistant Staphylococcus aureus Biofilm from the Antarctic Sponge Dendrilla membranosa. Organic Letters. June 3, 2016. Featured as ACS Editor’s Choice June 30th 2016; 90,000+ views in 2016; most viewed article from ACS. DOI: 10.1021/acs.orglett.6b00979.

  11. Nina Bionda, Renee M. Fleeman, César de la Fuente-Núñez, Maria C. Rodriguez, Fany Reffuveille, Lindsey N. Shaw, Irena Pastar, Stephen C. Davis, Robert E. W. Hancock, and Predrag Cudic. Identification of novel cyclic lipopeptides from a positional scanning combinatorial library with enhanced antibacterial and antibiofilm activites. Eur J Med Chem. January 27, 2016. DOI: 10.1016/j.ejmech.2015.11.032.

  12. Renee Fleeman, Travis M. LaVoi, Radleigh G. Santos, Angela Morales, Adel Nefzi, Gregory S. Welmaker, José L. Medina-Franco, Marc A. Giulianotti, Richard A. Houghten, and Lindsey N. Shaw. Combinatorial Libraries as a Tool for the Discovery of Novel, Broad-Spectrum Antibacterial Agents Targeting the ESKAPE Pathogens. J. Med. Chem. April 23, 2015. DOI: 10.1021/jm501628s.

  13. Van Horn K, Burda W, Fleeman RM, Manetsch R, Shaw L. Antibacterial Activity of a Series of N2,N4-Disubstituted Quinazoline-2,4-Diamines. JMedChem. April 10, 2014. DOI: 10.1021/jm500039e.

  14. Bionda N, Fleeman RM, Shaw LN, Cudic P. Effect of Ester to Amide or N-methyl Amide Substitution on Membrane Depolarization and Antibacterial Activity of Novel Cyclic Lipopeptides. ChemMedChem. August 8, 2013. DOI: 10.1002/cmdc.201300173.

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